**Paul Perco**

Latest

• Multimarker Panels in Diabetic Kidney Disease: The Way to Improved Clinical Trial Design and Clinical Practice?
• Synthetic lethality guiding selection of drug combinations in ovarian cancer
• Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast
• Validation of Plasma Biomarker Candidates for the Prediction of eGFR Decline in Patients With Type 2 Diabetes
• Validation of systems biology derived molecular markers of renal donor organ status associated with long term allograft function
• Endogenous factors and mechanisms of renoprotection and renal repair
• Molecular, histological, and clinical phenotyping of diabetic nephropathy: valuable complementary information?
• Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma
• Systems Biology-Derived Biomarkers to Predict Progression of Renal Function Decline in Type 2 Diabetes
• Validation of a protein panel for the noninvasive detection of recurrent non-muscle invasive bladder cancer
• Predictive Biomarkers for Linking Disease Pathology and Drug Effect
• Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer
• Metallothioneins and renal ageing
• Renal microRNA- and RNA-profiles in progressive chronic kidney disease
• Disease map-based biomarker selection and pre-validation for bladder cancer diagnostic
• Molecular disease presentation in diabetic nephropathy
• Drugs meeting the molecular basis of diabetic kidney disease: bridging from molecular mechanism to personalized medicine
• A panel of novel biomarkers representing different disease pathways improves prediction of renal function decline in type 2 diabetes
• Protein interactome of muscle invasive bladder cancer
• A 3-biomarker-panel predicts renal outcome in patients with proteinuric renal diseases
• From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action
• Mass spectrometric-bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides
• Molecular pathogenesis of post-transplant acute kidney injury: assessment of whole-genome mRNA and miRNA profiles
• Functional molecular units for guiding biomarker panel design
• Proteome-based systems biology analysis of the diabetic mouse aorta reveals major changes in fatty acid biosynthesis as potential hallmark in diabetes mellitus-associated vascular disease
• Using information content for expanding human protein coding gene interaction networks
• miRNA profiling discriminates types of rejection and injury in human renal allografts
• Molecular models of the cardiorenal syndrome
• Evaluation of the Zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles
• Increased renal versican expression is associated with progression of chronic kidney disease
• Data Graphs for Linking Clinical Phenotype and Molecular Feature Space
• Molecular Pathways and Crosstalk Characterizing the Cardiorenal Syndrome
• In-silico human genomics with GeneCards
• Linking molecular feature space and disease terms for the immunosuppressive drug rapamycin
• Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy
• Recurrence-free survival in prostate cancer is related to increased stromal TRAIL expression
• Mycophenolate Mofetil Associated Molecular Profiles and Diseases
• Computational analysis workflows for Omics data interpretation
• Data and knowledge management in cross-Omics research projects
• Computational Reconstruction of Protein Interaction Networks
• Integrative bioinformatics analysis of proteins associated with the cardiorenal syndrome
• Integrative analysis of -omics data and histologic scoring in renal disease and transplantation: Renal histogenomics
• Synthetic lethal hubs associated with vincristine resistant neuroblastoma
• Adaptive trimmed t-statistics for identifying predominantly high expression in a microarray experiment
• Molecular biomarker candidates of acute kidney injury in zero-hour renal transplant needle biopsies
• Steroid pretreatment of organ donors to prevent postischemic renal allograft failure: a randomized, controlled trial
• Linking transcriptomic and proteomic data on the level of protein interaction networks
• Natural Immunity Enhances the Activity of a DR5 Agonistic Antibody and Carboplatin in the Treatment of Ovarian Cancer
• The role of c-FLIPL in ovarian cancer: Chaperoning tumor cells from immunosurveillance and increasing their invasive potential
• Impaired metabolism in donor kidney grafts after steroid pretreatment
• Systems biology: Opening new avenues in clinical research
• Biomarkers in renal transplantation ischemia reperfusion injury
• Biocompatibility of peritoneal dialysis solutions determined by genomics of human leucocytes: a cross-over study
• Neuropilin-1 and neuropilin-2 are differentially expressed in human proteinuric nephropathies and cytokine-stimulated proximal tubular cells
• A dependency graph approach for the analysis of differential gene expression profiles
• Microarray and bioinformatics analysis of gene expression in experimental membranous nephropathy
• Histogenomics: association of gene expression patterns with histological parameters in kidney biopsies
• Molecular predictors for anaemia after kidney transplantation
• Biocompatibility of haemodialysis membranes determined by gene expression of human leucocytes: A crossover study
• Bortezomib-induced survival signals and genes in human proximal tubular cells
• The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces
• Present status at the Vienna Transplantation Center after four thousand renal transplantations
• Kidney injury molecule-1 as a biomarker of acute kidney injury in renal transplant recipients
• Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation
• Biomarker candidates for cardiovascular disease and bone metabolism disorders in chronic kidney disease: A systems biology perspective
• Analysis and prediction of protective continuous B-cell epitopes on pathogen proteins
• Linking the ovarian cancer transcriptome and immunome
• Influence of microvascular endothelial cells on transcriptional regulation of proximal tubular epithelial cells
• In vitro - Transcriptional response of polymorphonuclear leukocytes following contact with different antigens
• Characterization of protein-interaction networks in tumors
• Gene-expression profiles and age of donor kidney biopsies obtained before transplantation distinguish medium term graft function
• Gene expression and biomarkers in renal transplant ischemia reperfusion injury
• Gene expression profiles of human proximal tubular epithelial cells in proteinuric nephropathies
• Protein biomarkers associated with acute renal failure and chronic kidney disease
• Transforming omics data into context: bioinformatics on genomics and proteomics raw data
• Molecular signature of mice T lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade
• Identification of over-represented combinations of transcription factor binding sites in sets of co-expressed genes
• Transcriptional response in the unaffected kidney after contralateral hydronephrosis or nephrectomy
• Detection of coregulation in differential gene expression profiles
• Effect of tissue fixatives on telomere length determination by quantitative PCR
• Alterations in gene expression in cadaveric vs. live donor kidneys suggest impaired tubular counterbalance of oxidative stress at implantation
• Genome-wide gene-expression patterns of donor kidney biopsies distinguish primary allograft function
• Testing for the D zygosity with three different methods revealed altered Rhesus boxes and a new weak D type
• RHD sequencing: A new tool for decision making on transfusion therapy and provision of Rh prophylaxis